What significant work published in 1700 addressed the health issues of workers?

The work published in 1700 that specifically addressed the health issues of workers is often recognized as "The Disease of Workers." This title is significant because it represents one of the earliest attempts to systematically analyze and document the health conditions prevailing in the labor force during that era. It highlights the connection between working conditions and health, emphasizing the detrimental effects that various occupations could have on workers' well-being. This early publication laid the groundwork for future studies and developments in occupational health, making it a pivotal reference in the field.

While other options may suggest related themes or focus on aspects of laborers' health, "The Disease of Workers" is historically noted for its explicit examination of health issues specifically tied to workers, thus making it the most significant work in the context of this question.